MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging
نویسندگان
چکیده
منابع مشابه
Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging.
MicroPET II is a newly developed PET (positron emission tomography) scanner designed for high-resolution imaging of small animals. It consists of 17,640 LSO crystals each measuring 0.975 x 0.975 x 12.5 mm3, which are arranged in 42 contiguous rings, with 420 crystals per ring. The scanner has an axial field of view (FOV) of 4.9 cm and a transaxial FOV of 8.5 cm. The purpose of this study was to...
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UNLABELLED The microPET Focus is the latest generation microPET system dedicated to high-resolution animal imaging and incorporates several changes to enhance its performance. This study evaluated the basic performance of the scanner and compared it with the Primate (P4) and Rodent (R4) models. METHODS The system consists of 168 lutetium oxyorthosilicate (LSO) detectors arranged in 4 contiguo...
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The process of drug discovery and development requires substantial resources and time. The drug industry has tried to reduce costs by conducting appropriate animal studies together with molecular biological and genetic analyses. Basic science research has been limited to in vitro studies of cellular processes and ex vivo tissue examination using suitable animal models of disease. However, in th...
متن کاملPerformance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanner for animal imaging.
UNLABELLED A new dedicated PET scanner, microPET, was designed and developed at the University of California, Los Angeles, for imaging small laboratory animals. The goal was to provide a compact system with superior spatial resolution at a fraction of the cost of a clinical PET scanner. METHODS The system uses fiberoptic readout of individually cut lutetium oxyorthosilicate (LSO) crystals to ...
متن کاملPerformance measurement of the microPET focus 120 scanner.
UNLABELLED The microPET Focus 120 scanner is a third-generation animal PET scanner dedicated to rodent imaging. Here, we report the results of scanner performance testing. METHODS A (68)Ge point source was used to measure energy resolution, which was determined for each crystal and averaged. Spatial resolution was measured using a (22)Na point source with a nominal size of 0.25 mm at the syst...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2003
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/48/11/303